Metabolism Antibodies 2

GALC Rabbit Polyclonal Antibody (CAB3873)

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SKU:
CAB3873
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Metabolism
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
GALC
Research Use:
Metabolism
Frequently bought together:

Description

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GALC Antibody (CAB3873)

The GALC Antibody (CAB3873) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications such as Western blotting. By binding specifically to the GALC protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it a versatile tool for research in biochemistry and neurology.GALC, also known as galactocerebrosidase, is responsible for breaking down specific fats in the body, particularly within the nervous system.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:GALC Antibody
SKU:CAB3873
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:GGAY VLDD SDGL GREF DGIG AVSG GGAT SRLL VNYP EPYR SQIL DYLF KPNF GASL HILK VEIG GDGQ TTDG TEPS HMHY ALDE NYFR GYEW WLMK EAKK RNPN ITLI GLPW SFPG WLGK GFDW PYVN LQLT AYYV VTWI VGAK RYHD LDID YIGI WNER SYNA NYIK ILRK MLNY QGLQ RVKI IASD NLWE SISA SMLL DAEL FKVV DVIG AHYP GTHS AKDA KLTG KKLW SSED FSTL NSDM GAGC WGRI LNQN YING Y
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:GALC
Positive Sample:DU145, 293T, HepG2, A375, Mouse brain, Rat testis
Cellular Localization:Lysosome.
Calculated MW:77kDa
Observed MW:77kDa

This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Purification MethodAffinity purification
Gene ID2581
RRIDAB_2765354
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using GALC Rabbit pAb (CAB3873) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human kidney using GALC Rabbit pAb (CAB3873) at dilution of 1:200 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
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