Cell Biology Antibodies 13

HNRRabbit Polyclonal Antibody Rabbit Polyclonal Antibody (CAB17497)

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SKU:
CAB17497
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
ABBP1, HNRNPAB, HNRPAB
Research Use:
Cell Biology
Frequently bought together:

Description

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HNR Antibody Antibody (CAB17497)

The HNR Antibody Antibody (CAB17497) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, shows high specificity and reactivity towards human samples, making it ideal for use in Western blot applications. By binding to the HNRNPAB protein, this antibody enables researchers to detect and analyze the expression of HNRNPAB in various cell types.HNRNPAB, also known as heterogeneous nuclear ribonucleoprotein AB, plays a crucial role in mRNA splicing and stability, making it a key player in gene regulation.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:HNR Antibody Antibody
SKU:CAB17497
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MSEA GEEQ PMET TGAT ENGH EAVP EGES PAGA GTGA AAGA GGAT AAPP SGNQ NGAE GDQI NASK NEED AGKM FVGG LSWD TSKK DLKD YFTK FGEV VDCT IKMD PNTG RSRG FGFI LFKD AASV EKVL DQKE HRLD GRVI DPKK AMAM KKDP VKKI FVGG LNPE ATEE KIRE YFGE FGEI EAIE LPMD PKLN KRRG FVFI TFKE EEPV KKVL EKKF HTVS GSKC EIKV AQPK EVYQ QQQY GSGG RGNR NRGN RGSG GGGG GGGQ GSTN YGKS QRRG GHQN NYKP Y
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:100
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:ABBP1, HNRNPAB, HNRPAB
Positive Sample:HeLa, 293T, Mouse liver, Rat liver
Cellular Localization:Cytoplasm, Neuronal Ribonucleoprotein Granule, Nucleoplasm, Nucleus.
Calculated MW:36kDa
Observed MW:37kDa/41kDa

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Purification MethodAffinity purification
Gene ID3182
RRIDAB_2769821
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using HNRPAB Rabbit pAb (CAB17497) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Product ImageImmunofluorescence analysis of U-2 OS cells using HNRPAB Rabbit pAb (CAB17497) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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