Epigenetics & Nuclear Signaling Antibodies 3

BACH1 Rabbit Polyclonal Antibody (CAB5393)

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SKU:
CAB5393
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse
Synonyms:
BACH-1, BTBD24, BACH1
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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BACH1 Antibody (CAB5393)

The BACH1 Antibody (CAB5393) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications.BACH1 is known to play a critical role in maintaining cellular homeostasis by controlling the expression of genes involved in antioxidant defense mechanisms and DNA repair processes. Dysregulation of BACH1 has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions.

This antibody is validated for use in WB, IP, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:BACH1 Antibody
SKU:CAB5393
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MSLS ENSV FAYE SSVH STNV LLSL NDQR KKDV LCDV TIFV EGQR FRAH RSVL AACS SYFH SRIV GQAD GELN ITLP EEVT VKGF EPLI QFAY TAKL ILSK ENVD EVCK CVEF LSVH NIEE SCFQ FLKF KFLD STAD QQEC PRKK CFSS HCQK TDLK LSLL DQRD LETD EVEE FLEN KNVQ TPQC KLRR YQGN AKAS PPLQ DSAS QTYE SMCL EKDA ALAL PSLC PKYR KFQK AFGT DRVR TGES SVKD IHAS VQPN ERSE NECL GGVP ECRD LQVM LKCD ESKL AMEP EETK KDPA SQCP TEKS EVTP FPHN SSID PHGL
Tested Applications:WB IP ELISA
Recommended Dilution:
WB1:1000 - 1:5000
IP0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:BACH-1, BTBD24, BACH1
Positive Sample:HEL, K-562
Cellular Localization:Nucleus.
Calculated MW:82kDa
Observed MW:100-110kDa

This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene.

Purification MethodAffinity purification
Gene ID571
RRIDAB_2766202
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from HEL cells, using BACH1 Rabbit pAb (CAB5393) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
Product ImageImmunoprecipitation analysis of 300 μg extracts of K-562 cells using 3 μg BACH1 antibody (CAB5393). Western blot was performed from the immunoprecipitate using BACH1 antibody (CAB5393) at a dilution of 1:600.
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