YB-1/YBX1 Polyclonal Antibody (CAB6799)

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SKU:
CAB6799
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IF
Reactivity:
Human, Mouse, Rat
Synonyms:
YB1, BP-8, CSDB, DBPB, YB-1, CBF-A, CSDA2, EFI-A, NSEP1, NSEP-1, MDR-NF1, YB-1/YBX1
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Description

system_update_altDatasheetsystem_update_altMSDS

YB-1/YBX1 Polyclonal Antibody (CAB6799)

The YB-1/YBX1 Polyclonal Antibody (CAB6799) is a high-quality antibody developed for reliable detection and analysis of target proteins. YB-1 is a multifunctional protein involved in regulating gene expression, DNA repair, and cell proliferation. This antibody, produced in rabbits, specifically binds to the YB-1 protein in human samples, making it ideal for use in Western blot applications.YB-1 has been implicated in cancer progression, drug resistance, and metastasis, making it a target of interest in cancer research.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:YB-1/YBX1 Polyclonal Antibody
SKU:CAB6799
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MSSE AETQ QPPA APPA APAL SAAD TKPG TTGS GAGS GGPG GLTS AAPA GGDK KVI
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
IF/ICC1:20 - 1:50
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:YB1, BP-8, CSDB, DBPB, YB-1, CBF-A, CSDA2, EFI-A, NSEP1, NSEP-1, MDR-NF1, YB-1/YBX1
Positive Sample:293T
Cellular Localization:Cytoplasm, Cytoplasmic Granule, Nucleus, Secreted.
Calculated MW:36kDa
Observed MW:50kDa

This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes.

Purification MethodAffinity purification
Gene ID4904
RRIDAB_2767381
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from 293T cells, using YB-1/YBX1 Rabbit pAb (CAB6799). Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
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