Epigenetics & Nuclear Signaling Antibodies 1

TRIM24 Rabbit Polyclonal Antibody (CAB10546)

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SKU:
CAB10546
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Synonyms:
PTC6, TF1A, TIF1, RNF82, TIF1A, hTIF1, TIF1ALPHA, TRIM24
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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TRIM24 Antibody (CAB10546)

The TRIM24 Antibody (CAB10546) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is specifically designed to target Trim24 in human samples, making it an ideal choice for Western blot applications.Trim24, also known as TIF-1α, is a transcriptional co-regulator that plays a key role in various cellular processes, including development, metabolism, and immune response. Dysregulation of Trim24 has been linked to cancer, making it a potential therapeutic target for cancer treatment.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:TRIM24 Antibody
SKU:CAB10546
Size:20μL, 100μL
Reactivity:Human
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:DGKA FGSP MIDL SSPV GGSY NLPS LPDI DCSS TIML DNIV RKDT NIDH GQPR PPSN RTVQ SPNS SVPS PGLA GPVT MTSV HPPI RSPS ASSV GSRG SSGS SSKP AGAD STHK VPVV MLEP IRIK QENS GPPE NYDF PVVI VKQE SDEE SRPQ NANY PRSI LTSL LLNS SQSS TSEE TVLR SDAP DSTG DQPG LHQD NSSN GKSE WLDP SQKS PLHV GETR K
Tested Applications:WB ELISA
Recommended Dilution:
WB1:1000 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PTC6, TF1A, TIF1, RNF82, TIF1A, hTIF1, TIF1ALPHA, TRIM24
Positive Sample:293T, HeLa
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:117kDa
Observed MW:117kDa

The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Purification MethodAffinity purification
Gene ID8805
RRIDAB_2758087
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using TRIM24 Rabbit pAb (CAB10546) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
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