Cell Cycle Antibodies 2

TPPP/p25 Rabbit Polyclonal Antibody (CAB8574)

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SKU:
CAB8574
Product Type:
Antibody
Applications:
WB
Applications:
IHC
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Cycle
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
p24, p25, TPPP1, TPPP/p25, p25alpha
Research Use:
Cell Cycle
Frequently bought together:

Description

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TPPP/p25 Antibody (CAB8574)

The TPPP/p25 Antibody (CAB8574) is a high-quality antibody developed for reliable detection and analysis of target proteins. TPPP, also known as tubulin polymerization promoting protein, is involved in microtubule dynamics and has been implicated in neurodegenerative diseases such as Parkinson's and Alzheimer's.This polyclonal antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to the TPPP protein, this antibody enables accurate detection and analysis in different cell types, making it an ideal choice for studies in neuroscience and neurology.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:TPPP/p25 Antibody
SKU:CAB8574
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MADK AKPA KAAN RTPP KSPG DPSK DRAA KRLS LESE GAGE GAAA SPEL SALE EAFR RFAV HGDA RATG REMH GKNW SKLC KDCQ VIDG RNVT VTDV DIVF SKIK GKSC RTIT FEQF QEAL EELA KKRF KDKS SEEA VREV HRLI EGKA PIIS GVTK AISS PTVS RLTD TTKF TGSH KERF DPSG KGKG KAGR VDLV DESG YVSG YKHA GTYD QKVQ GGK
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:p24, p25, TPPP1, TPPP/p25, p25alpha
Positive Sample:Jurkat, Mouse brain, Mouse pancreas, Rat brain
Cellular Localization:Cytoplasm, Nucleus, Cytoskeleton.
Calculated MW:24kDa
Observed MW:24kDa

Enables several functions, including GTPase activity; magnesium ion binding activity; and protein homodimerization activity. Involved in several processes, including microtubule cytoskeleton organization; negative regulation of tubulin deacetylation; and positive regulation of protein polymerization. Located in several cellular components, including mitochondrion; mitotic spindle; and perinuclear region of cytoplasm. Colocalizes with microtubule and microtubule bundle.

Purification MethodAffinity purification
Gene ID11076
RRIDAB_2772694
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using TPPP/p25 Rabbit pAb (CAB8574) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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