Epigenetics & Nuclear Signaling Antibodies 1

TLE1 Rabbit Polyclonal Antibody (CAB13360)

(No reviews yet) Write a Review
SKU:
CAB13360
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Synonyms:
ESG, ESG1, GRG1, TLE-1, TLE1
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

TLE1 Antibody (CAB13360)

The TLE1 Antibody (CAB13360) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for use in Western blot applications.TLE1 is a key player in the regulation of gene expression and has been implicated in numerous diseases, including cancer. By targeting TLE1, researchers can gain insights into the mechanisms of cancer development and progression, potentially leading to the development of novel therapeutic strategies.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.

Product Name:TLE1 Antibody
SKU:CAB13360
Size:20μL, 100μL
Reactivity:Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:DPSS PRAS PAHS PREN GIDK NRLL KKDA SSSP ASTA SSAS STSL KSKE MSLH EKAS TPVL KSST PTPR SDMP TPGT SATP GLRP GLGK PPAI DPLV NQAA
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:ESG, ESG1, GRG1, TLE-1, TLE1
Positive Sample:Mouse liver
Cellular Localization:Nucleus.
Calculated MW:83kDa
Observed MW:83kDa

Enables identical protein binding activity and transcription corepressor activity. Involved in negative regulation of I-kappaB kinase/NF-kappaB signaling; negative regulation of anoikis; and regulation of gene expression. Located in cytosol and nucleoplasm. Part of beta-catenin-TCF complex.

Purification MethodAffinity purification
Gene ID7088
RRIDAB_2760218
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from Mouse liver, using TLE1 Rabbit pAb (CAB13360) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
View AllClose

0 Reviews

View AllClose

Related Products