Metabolism Antibodies 2

ROR1 Rabbit Polyclonal Antibody (CAB3315)

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SKU:
CAB3315
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Metabolism
Antibody Type:
Polyclonal Antibody
Reactivity:
Rat
Synonyms:
NTRKR1, dJ537F10.1, ROR1
Research Use:
Metabolism
Frequently bought together:

Description

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ROR1 Antibody (CAB3315)

The ROR1 Antibody (CAB3315) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications.ROR1 is a cell surface protein that is implicated in various cellular processes, including cell proliferation, survival, and migration. It plays a role in cancer development and has been identified as a potential therapeutic target in certain types of cancer.By targeting the ROR1 protein, researchers can investigate its role in cancer progression and potentially develop targeted therapies for ROR1-expressing cancers.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Rat samples.

Product Name:ROR1 Antibody
SKU:CAB3315
Size:20μL, 100μL
Reactivity:Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:ARGA AAQE TELS VSAE LVPT SSWN ISSE LNKD SYLT LDEP MNNI TTSL GQTA ELHC KVSG NPPP TIRW FKND APVV QEPR RLSF RSTI YGSR LRIR NLDT TDTG YFQC VATN GKEV VSST GVLF VKFG PPPT ASPG YSDE YEED GFCQ PYRG IACA RFIG NRTV YMES LHMQ GEIE NQIT AAFT MIGT SSHL SDKC SQFA IPSL CHYA FPYC DETS SVPK PRDL CRDE CEIL ENVL CQTE YIFA RSNP MILM RLKL PNCE DLPQ PESP EAAN CIRI GIPM ADPI NKNH KCYN STGV DYRG TVSV TKSG RQCQ PWNS QYPH THTF TALR FPEL NGGH SYCR NPGN QKEA PWCF TLDE NFKS DLCD IPAC DSKD SKEK NKME
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:NTRKR1, dJ537F10.1, ROR1
Positive Sample:Rat uterus
Cellular Localization:Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:104kDa
Observed MW:135kDa

This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Purification MethodAffinity purification
Gene ID4919
RRIDAB_2765045
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from Rat uterus, using ROR1 Rabbit pAb (CAB3315) at 1:800 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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