Epigenetics & Nuclear Signaling Antibodies 1

POLR1C Rabbit Polyclonal Antibody (CAB0269)

(No reviews yet) Write a Review
SKU:
CAB0269
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Synonyms:
AC40, RPA5, TCS3, HLD11, RPA39, RPA40, RPAC1, RPC40, POLR1C
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

POLR1C Antibody (CAB0269)

The POLR1C Antibody (CAB0269) is a high-quality antibody developed for reliable detection and analysis of target proteins. The antibody, generated in rabbits, is highly reactive with human samples and is validated for use in various applications such as Western blot and immunohistochemistry.POLR1C is a key component of the RNA polymerase I complex, essential for the synthesis of ribosomal RNA and protein translation. Dysregulation of POLR1C has been associated with various diseases, including cancer and developmental disorders.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:POLR1C Antibody
SKU:CAB0269
Size:20μL, 100μL
Reactivity:Human
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MAAS QAVE EMRS RVVL GEFG VRNV HTTD FPGN YSGY DDAW DQDR FEKN FRVD VVHM DENS LEFD MVGI DAAI ANAF RRIL LAEV PTMA VEKV LVYN NTSI VQDE ILAH RLGL IPIH ADPR LFEY RNQG DEEG TEID TLQF RLQV RCTR NPHA AKDS SDPN ELYV NHKV YTRH MTWI PLGN QADL FPEG TIRP VHDD ILIA
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:AC40, RPA5, TCS3, HLD11, RPA39, RPA40, RPAC1, RPC40, POLR1C
Positive Sample:K-562, 293T, MCF7
Cellular Localization:Nucleus.
Calculated MW:39kDa
Observed MW:39kDa

The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID9533
RRIDAB_2757082
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using POLR1C Rabbit pAb (CAB0269) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
View AllClose

0 Reviews

View AllClose

Related Products