Immunology Antibodies 2

PIBF1 Rabbit Polyclonal Antibody (CAB3072)

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SKU:
CAB3072
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
PIBF, CEP90, JBTS33, C13orf24, PIBF1
Research Use:
Immunology
Frequently bought together:

Description

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PIBF1 Antibody (CAB3072)

The PIBF1 Antibody (CAB3072) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for Western blot analyses.PIBF1, also known as progesterone-induced blocking factor 1, is implicated in regulating immune responses during pregnancy and is associated with promoting maternal-fetal tolerance. Its expression has been linked to conditions such as recurrent miscarriage and autoimmune disorders, making it a significant target for further investigation.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:PIBF1 Antibody
SKU:CAB3072
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:MSRK ISKE SKKV NISS SLES EDIS LETT VPTD DISS SEER EGKV RITR QLIE RKEL LHNI QLLK IELS QKTM MIDN LKVD YLTK IEEL EEKL NDAL HQKQ
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:100
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PIBF, CEP90, JBTS33, C13orf24, PIBF1
Positive Sample:Mouse heart
Cellular Localization:Cytoplasm, Nucleus, Secreted, Secreted, Centriolar Satellite, Centrosome, Cytoskeleton, Microtubule Organizing Center.
Calculated MW:90kDa
Observed MW:100kDa

This gene encodes a protein that is induced by the steroid hormone progesterone and plays a role in the maintenance of pregnancy. The encoded protein regulates multiple facets of the immune system to promote normal pregnancy including cytokine synthesis, natural killer (NK) cell activity, and arachidonic acid metabolism. Low serum levels of this protein have been associated with spontaneous pre-term labor in humans. This protein may promote the proliferation, migration and invasion of glioma.

Purification MethodAffinity purification
Gene ID10464
RRIDAB_2764875
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from mouse heart, using PIBF1 Rabbit pAb (CAB3072) at 1:400 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human rectal cancer using PIBF1 Rabbit pAb (CAB3072) at dilution of 1:200 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat testis using PIBF1 Rabbit pAb (CAB3072) at dilution of 1:200 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
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