Cell Biology Antibodies 10

MSLN Rabbit Polyclonal Antibody (CAB6183)

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SKU:
CAB6183
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse
Synonyms:
MPF, SMRP, Mesothelin
Research Use:
Cell Biology
Frequently bought together:

Description

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MSLN Antibody (CAB6183)

The MSLN Antibody (CAB6183) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the mesothelin protein, enabling accurate detection and analysis in a variety of cell types.Mesothelin is a promising biomarker and potential target for cancer therapy, making this antibody ideal for studies in oncology and tumor biology.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:MSLN Antibody
SKU:CAB6183
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:EVEK TACP SGKK AREI DESL IFYK KWEL EACV DAAL LATQ MDRV NAIP FTYE QLDV LKHK LDEL YPQG YPES VIQH LGYL FLKM SPED IRKW NVTS LETL KALL EVNK GHEM SPQA PRRP LPQV ATLI DRFV KGRG QLDK DTLD TLTA FYPG YLCS LSPE ELSS VPPS SIWA VRPQ DLDT CDPR QLDV LYPK ARLA FQNM NGSE YFVK IQSF LGGA PTED LKAL SQQN VSMD LATF MKLR TDAV LPLT VAEV QKLL GPHV EGLK AEER HRPV RDWI LRQR QDDL DTLG LGLQ GGIP NGYL VLDL SMQE ALS
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:MPF, SMRP, Mesothelin
Positive Sample:OVCAR3
Cellular Localization:Cell Membrane, Gpi-Anchor, Golgi Apparatus, Lipid-Anchor, Secreted.
Calculated MW:69kDa
Observed MW:45kDa

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Purification MethodAffinity purification
Gene ID10232
RRIDAB_2766796
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from OVCAR3 cells, using (CAB6183) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
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