Immunology Antibodies 1

LTF Rabbit Polyclonal Antibody (CAB12902)

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SKU:
CAB12902
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
Reactivity:
Human, Mouse, Rat
Synonyms:
LF, HLF2, GIG12, HEL110, LTF
Research Use:
Immunology
Frequently bought together:

Description

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LTF Antibody (CAB12902)

The LTF Antibody (CAB12902) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot experiments.LTF, also known as lactoferrin, is a key player in the body's defense against microbial infections by sequestering iron, which is essential for bacterial growth. Additionally, LTF possesses anti-inflammatory and immunomodulatory properties, making it a promising target for research in fields such as immunology, microbiology, and nutrition.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:LTF Antibody
SKU:CAB12902
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:RRRS VQWC AVSQ PEAT KCFQ WQRN MRKV RGPP VSCI KRDS PIQC IQAI AENR ADAV TLDG GFIY EAGL APYK LRPV AAEV YGTE RQPR THYY AVAV VKKG GSFQ LNEL QGLK SCHT GLRR TAGW NVPI GTLR PFLN WTGP PEPI EAAV ARFF SASC VPGA DKGQ FPNL CRLC AGTG ENKC AFSS QEPY FSYS GAFK CLRD GAGD VAFI REST VFED LSDE AERD EYEL LCPD NTRK PVDK FKDC HLAR VPSH AVVA RSVN GKED AIWN LLRQ AQEK FGKD KSPK FQLF GSPS GQKD LLFK DSAI GFSR VPPR IDSG LYLG SGYF TAIQ NLRK
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:100 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:LF, HLF2, GIG12, HEL110, LTF
Positive Sample:Rat lung
Cellular Localization:Cytoplasm, Cytoplasmic Granule, Nucleus, Secreted.
Calculated MW:78kDa
Observed MW:85kDa

This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Activity against both DNA and RNA viruses has been found, including activity against SARS-CoV-2, and HIV.

Purification MethodAffinity purification
Gene ID4057
RRIDAB_2759747
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from Rat lung, using LTF Rabbit pAb (CAB12902) at 1:1500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat kidney using LTF Rabbit pAb (CAB12902) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Mouse kidney using LTF Rabbit pAb (CAB12902) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
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