Cell Biology Antibodies 5

NLRP12 Rabbit Polyclonal Antibody (CAB14519)

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SKU:
CAB14519
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Synonyms:
RNO, PAN6, RNO2, FCAS2, NALP12, PYPAF7, CLR19.3, NLRP12
Research Use:
Cell Biology
Frequently bought together:

Description

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NLRP12 Antibody (CAB14519)

The NLRP12 Antibody (CAB14519) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the NLRP12 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it well-suited for investigations in immunology and inflammatory disease research.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Rat samples.

Product Name:NLRP12 Antibody
SKU:CAB14519
Size:20μL, 100μL
Reactivity:Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:WLKI CRLT AAAC DELA STLS VNQS LREL DLSL NELG DLGV LLLC EGLR HPTC KLQT LRLG ICRL GSAA CEGL SVVL QANH NLRE LDLS FNDL GDWG LWLL AEGL QHPA CRLQ KLWL DSCG LTAK ACEN LYFT LGIN QTLT DLYL TNNA LGDT GVRL LCKR LSHP GCKL RVLW LFGM DLNK MTHS RLAA LRVT KPYL DIGC
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:RNO, PAN6, RNO2, FCAS2, NALP12, PYPAF7, CLR19.3, NLRP12
Positive Sample:Rat spleen
Cellular Localization:Cytoplasm.
Calculated MW:120kDa
Observed MW:120kDa

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID91662
RRIDAB_2761394
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from rat spleen, using NLRP12 Rabbit pAb (CAB14519) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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