Epigenetics & Nuclear Signaling Antibodies 3

LOXL2 Rabbit Polyclonal Antibody (CAB14638)

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SKU:
CAB14638
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse, Rat
Synonyms:
LOR, LOR2, WS9-14, LOXL2
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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LOXL2 Antibody (CAB14638)

The LOXL2 Antibody (CAB14638) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it suitable for use in Western blot applications. By targeting the LOXL2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential asset for studies in cancer research, fibrosis, and tissue remodeling.LOXL2, a member of the lysyl oxidase enzyme family, plays a crucial role in the regulation of extracellular matrix organization and crosslinking of collagen and elastin fibers.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:LOXL2 Antibody
SKU:CAB14638
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:ANVA KIQL RLAG QKRK HSEG RVEV YYDG QWGT VCDD DFSI HAAH VVCR ELGY VEAK SWTA SSSY GKGE GPIW LDNL HCTG NEAT LAAC TSNG WGVT DCKH TEDV GVVC SDKR IPGF KFDN SLIN QIEN LNIQ VEDI RIRA ILST YRKR TPVM EGYV EVKE GKTW KQIC DKHW TAKN SRVV CGMF GFPG ERTY NTKV YKMF ASRR KQRY WPFS MDCT GTEA HISS CKLG PQVS LDPM KNVT
Tested Applications:WB ELISA
Recommended Dilution:
WB1:100 - 1:500
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:LOR, LOR2, WS9-14, LOXL2
Positive Sample:A-549, Mouse heart, Rat kidney
Cellular Localization:Chromosome, Nucleus, Secreted, Basement Membrane, Extracellular Matrix, Extracellular Space.
Calculated MW:87kDa
Observed MW:100kDa

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Purification MethodAffinity purification
Gene ID4017
RRIDAB_2761513
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using LOXL2 Rabbit pAb (CAB14638) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageWestern blot analysis of lysates from Rat kidney, using LOXL2 Rabbit pAb (CAB14638) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 180s.
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