Cell Biology Antibodies 9

LGI1 Rabbit Polyclonal Antibody (CAB5408)

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SKU:
CAB5408
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
EPT, ETL1, ADLTE, ADPAEF, ADPEAF, IB1099, EPITEMPIN, LGI1
Research Use:
Cell Biology
Frequently bought together:

Description

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LGI1 Antibody (CAB5408)

The LGI1 Antibody (CAB5408) is a high-quality antibody developed for reliable detection and analysis of target proteins. Produced in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to LGI1, this antibody allows for precise detection and analysis of the protein in various cell types, making it essential for studies in neuroscience and neurological disorders.LGI1 is a secreted protein that plays a crucial role in maintaining neuronal excitability and synaptic transmission. Mutations in LGI1 have been associated with various forms of epilepsy, highlighting its importance in brain function and disease.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:LGI1 Antibody
SKU:CAB5408
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:QLFG GSHI YKRD SFAN KFIK IQDI EILK IRKP NDIE TFKI ENNW YFVV ADSS KAGF TTIY KWNG NGFY SHQS LHAW YRDT DVEY LEIV RTPQ TLRT PHLI LSSS SQRP VIYQ WNKA TQLF TNQT DIPN MEDV YAVK HFSV KGDV YICL TRFI GDSK VMKW GGSS FQDI QRMP SRGS MVFQ PLQI NNYQ YAIL GSDY SFTQ VYNW DAEK AKFV KFQE LNVQ APRS FTHV SINK RNFL FASS FKGN TQIY KHVI VDLS A
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:EPT, ETL1, ADLTE, ADPAEF, ADPEAF, IB1099, EPITEMPIN, LGI1
Positive Sample:U-87MG, HeLa, Mouse brain, Rat brain
Cellular Localization:Cell Junction, Secreted, Synapse.
Calculated MW:64kDa
Observed MW:64kDa

This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID9211
RRIDAB_2766216
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using LGI1 Rabbit pAb (CAB5408) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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