Developmental Biology

Islet1 Rabbit Polyclonal Antibody (CAB6383)

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SKU:
CAB6383
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
Isl-1, ISLET1, Islet1
Research Use:
Developmental Biology
Frequently bought together:

Description

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Islet1 Antibody (CAB6383)

The Islet1 Antibody (CAB6383) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blotting applications. By targeting the ISL1 protein, researchers can gain valuable insights into its role in various cellular processes, making it an ideal choice for studies in developmental biology and regenerative medicine.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:Islet1 Antibody
SKU:CAB6383
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MGDM GDPP KKKR LISL CVGC GNQI HDQY ILRV SPDL EWHA ACLK CAEC NQYL DESC TCFV RDGK TYCK RDYI RLYG IKCA KCSI GFSK NDFV MRAR SKVY HIEC FRCV ACSR QLIP GDEF ALRE DGLF CRAD HDVV ERAS LGAG DPLS PLHP ARPL QMAA EPIS ARQP ALRP HVHK QPEK TTRV RTVL NEKQ LHTL RTCY AANP RPDA LMKE QLVE MTGL SPRV IRVW FQNK RCKD KKRS IMMK QLQQ QQPN DKTN IQGM TGTP MVAA SPER HDGG LQAN PVEV QSYQ PPWK VLSD FALQ SDID QPAF QQLV NFSE GGPG SNST GSEV ASMS SQLP DTPN SMVA SPIE A
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:Isl-1, ISLET1, Islet1
Positive Sample:HeLa, SH-SY5Y, Mouse thymus, Rat thymus
Cellular Localization:Nucleus.
Calculated MW:39kDa
Observed MW:50kDa

This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

Purification MethodAffinity purification
Gene ID3670
RRIDAB_2766985
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using Islet1 Rabbit pAb (CAB6383) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
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