Signal Transduction Antibodies 1

GABRA3 Rabbit Polyclonal Antibody (CAB11636)

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SKU:
CAB11636
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
Reactivity:
Human, Mouse, Rat
Synonyms:
EPILX2, GABRA3
Research Use:
Signal Transduction
Frequently bought together:

Description

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GABRA3 Antibody (CAB11636)

The GABRA3 Antibody (CAB11636) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly sensitive in detecting Gabra3 in human samples and has been validated for use in Western blot applications.Gabra3 is known for its involvement in mediating the effects of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain, making it a key player in the regulation of inhibitory neurotransmission. Dysregulation of Gabra3 has been linked to various neurological disorders, including epilepsy, anxiety disorders, and alcohol addiction.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:GABRA3 Antibody
SKU:CAB11636
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:QGES RRQE PGDF VKQD IGGL SPKH APDI PDDS TDNI TIFT RILD RLLD GYDN RLRP GLGD AVTE VKTD IYVT SFGP VSDT DMEY TIDV FFRQ TWHD ERLK FDGP MKIL PLNN LLAS KIWT PDTF FHNG KKSV AHNM TTPN KLLR LVDN GTLL YTMR LTIH AECP MHLE DFPM DVHA CPLK FGSY AYTT AEVV YSWT LGKN KSVE VAQD GSRL NQYD LLGH VVGT EIIR SSTG EYVV MTTH FHLK RKIG
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:EPILX2, GABRA3
Positive Sample:SH-SY5Y, Mouse kidney, Rat liver
Cellular Localization:Cell Junction, Cell Membrane, Multi-Pass Membrane Protein, Postsynaptic Cell Membrane, Synapse.
Calculated MW:55kDa
Observed MW:55kDa

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.

Purification MethodAffinity purification
Gene ID2556
RRIDAB_2758655
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using GABRA3 Rabbit pAb (CAB11636) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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