Cell Biology Antibodies 1

CACNA1E Rabbit Polyclonal Antibody (CAB10203)

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SKU:
CAB10203
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
BII, CACH6, DEE69, gm139, Cav2.3, EIEE69, CACNL1A6, CACNA1E
Research Use:
Cell Biology
Frequently bought together:

Description

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CACNA1E Antibody (CAB10203)

The CACNA1E Antibody (CAB10203) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.CACNA1E is a voltage-gated calcium channel involved in neurotransmitter release, neuronal excitability, and synaptic plasticity. Dysregulation of CACNA1E has been linked to neurological disorders such as epilepsy, ataxia, and developmental delay.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:CACNA1E Antibody
SKU:CAB10203
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:PSSM RRSF STIR DKRS NSSW LEEF SMER SSEN TYKS RRRS YHSS LRLS AHRL NSDS GHKS DTHR SGGR ERGR SKER KHLL SPDV SRCN SEER GTQA DWES PERR QSRS PSEG RSQT PNRQ GTGS LSES SIPS VSDT STPR RSRR QLPP VPPK PRPL LSYS SLIR HAGS ISPP ADGS EEGS PLTS QALE SNNA CLTE SSNS PHPQ QSQH ASPQ RYIS EPYL ALHE DSHA SDCG EEET LTFE AAVA TSLG RSNT IGSA PPLR HSWQ MPNG HYRR RRRG GPGP GMMC GAVN NLLS DTEE DDKC
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:BII, CACH6, DEE69, gm139, Cav2.3, EIEE69, CACNL1A6, CACNA1E
Positive Sample:U-87MG, 293T, Mouse brain, Mouse liver, Rat brain
Cellular Localization:Membrane, Multi-Pass Membrane Protein.
Calculated MW:262kDa
Observed MW:290kDa

Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Purification MethodAffinity purification
Gene ID777
RRIDAB_2757725
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using CACNA1E Rabbit pAb (CAB10203) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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