Developmental Biology

ZP1 Rabbit Polyclonal Antibody (CAB10776)

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SKU:
CAB10776
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
OOMD, ZPB1, OOMD1, HEL163, OZEMA1, ZP1
Research Use:
Developmental Biology
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Description

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ZP1 Antibody (CAB10776)

The ZP1 Antibody (CAB10776) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the ZP1 protein, this antibody allows for the detection and analysis of ZP1 in a variety of cell types, making it an excellent choice for studies in molecular biology and cell signaling research.ZP1, also known as zona pellucida protein 1, is essential for proper fertilization and embryo development. Its role in mediating sperm-egg interactions makes it a key target for research in reproductive biology and fertility treatments.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:ZP1 Antibody
SKU:CAB10776
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:AGDQ LIYE NWLV SGIH IQKG PQGS ITRD STFQ LHVR CVFN ASDF LPIQ ASIF PPPS PAPM TQPG PLRL ELRI AKDE TFSS YYGE DDYP IVRL LREP VHVE VRLL QRTD PNLV LLLH QCWG APSA NPFQ QPQW PILS DGCP FKGD SYRT QMVA LDGA TPFQ SHYQ RFTV ATFA LLDS GSQR ALRG LVYL FCST SACH TSGL ETCS TACS TGTT RQRR SSGH RNDT ARPQ DIVS SPGP VGFE DSYG QEPT LGPT DSNG NSSL RPLL WAVL LLP
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:OOMD, ZPB1, OOMD1, HEL163, OZEMA1, ZP1
Positive Sample:OVCAR8, OVCAR3, SKOV3, NCI-H460, A-549, Mouse lung, Rat ovary, Rat lung
Cellular Localization:Cell Membrane, Secreted, Single-Pass Type I Membrane Protein, Extracellular Matrix, Extracellular Space.
Calculated MW:70kDa
Observed MW:70kDa

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene ensures the structural integrity of the zona pellucida. Mutations in this gene are a cause of oocyte maturation defect and infertility.

Purification MethodAffinity purification
Gene ID22917
RRIDAB_2758213
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using ZP1 Rabbit pAb (CAB10776) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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