Cell Death Antibodies 2

GZMA Rabbit Polyclonal Antibody (CAB6231)

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SKU:
CAB6231
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
Reactivity:
Human, Mouse, Rat
Synonyms:
HFSP, CTLA3, GZMA
Research Use:
Cell Death
Frequently bought together:

Description

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GZMA Antibody (CAB6231)

The GZMA Antibody (CAB6231) is a high-quality antibody developed for reliable detection and analysis of target proteins. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. By targeting the Granzyme A protein, researchers can detect and analyze its presence in various cell types, making it a versatile tool for studies in immunology and cancer research.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:GZMA Antibody
SKU:CAB6231
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:IIGG NEVT PHSR PYMV LLSL DRKT ICAG ALIA KDWV LTAA HCNL NKRS QVIL GAHS ITRE EPTK QIML VKKE FPYP CYDP ATRE GDLK LLQL MEKA KINK YVTI LHLP KKGD DVKP GTMC QVAG WGRT HNSA SWSD TLRE VNIT IIDR KVCN DRNH YNFN PVIG MNMV CAGS LRGG RDSC NGDS GSPL LCEG VFRG VTSF GLEN KCGD PRGP GVYI LLSK KHLN WIIM TIKG AV
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:HFSP, CTLA3, GZMA
Positive Sample:NK-92, HeLa(Negative control)
Cellular Localization:Cytoplasmic Granule, Secreted.
Calculated MW:29kDa
Observed MW:28kDa

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.

Purification MethodAffinity purification
Gene ID3001
RRIDAB_2766840
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates, using GZMA Rabbit pAb (CAB6231) at 1:2500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageImmunofluorescence analysis of U2OS cells using GZMA Rabbit pAb (CAB6231) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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