Epigenetics & Nuclear Signaling Antibodies 1

WDR5 Rabbit Polyclonal Antibody (CAB13582)

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SKU:
CAB13582
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Synonyms:
BIG3, SWD3, BIG-3, CFAP89, WDR5
Research Use:
Epigenetics and Nuclear Signaling
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Description

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WDR5 Antibody (CAB13582)

The WDR5 Antibody (CAB13582) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the WDR5 protein, researchers can accurately detect and analyze WDR5 expression in various cell types, making it a versatile tool for studies in epigenetics and gene regulation.WDR5 is a key component of the SET1/MLL histone methyltransferase complex, crucial for the maintenance of proper gene expression and cellular function.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:WDR5 Antibody
SKU:CAB13582
Size:20μL, 100μL
Reactivity:Human
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MATE EKKP ETEA ARAQ PTPS SSAT QSKP TPVK PNYA LKFT LAGH TKAV SSVK FSPN GEWL ASSS ADKL IKIW GAYD GKFE KTIS GHKL GISD VAWS SDSN LLVS ASDD KTLK IWDV SSGK CLKT LKGH SNYV FCCN FNPQ SNLI VSGS FDES VRIW DVKT GKCL KTLP AHSD PVSA VHFN RDGS LIVS SSYD GLCR IWDT ASGQ CLKT LIDD DNPP VSFV KFSP NGKY ILAA TLDN TLKL WDYS KGKC LKTY TGHK NEKY CIFA NFSV TGGK WIVS GSED NLVY IWNL QTKE IVQK LQGH TDVV ISTA CHPT ENII ASAA LEND KTIK LWKS DC
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:BIG3, SWD3, BIG-3, CFAP89, WDR5
Positive Sample:HeLa
Cellular Localization:Nucleus.
Calculated MW:37kDa
Observed MW:37kDa

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.

Purification MethodAffinity purification
Gene ID11091
RRIDAB_2760444
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from HeLa cells, using WDR5 Rabbit pAb (CAB13582) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
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