Signal Transduction Antibodies 3

UBE2H Rabbit Polyclonal Antibody (CAB7344)

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SKU:
CAB7344
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
Reactivity:
Human, Mouse, Rat
Synonyms:
GID3, UBC8, UBCH, UBCH2, E2-20K, UBE2H
Research Use:
Signal Transduction
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

UBE2H Antibody (CAB7344)

The UBE2H Antibody (CAB7344) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples, making it suitable for a broad range of applications including Western blotting and immunohistochemistry.UBE2H plays a crucial role in mediating the transfer of ubiquitin molecules to target proteins, marking them for degradation or altering their function. Dysregulation of ubiquitination processes has been linked to various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:UBE2H Antibody
SKU:CAB7344
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MSSP SPGK RRMD TDVV KLIE SKHE VTIL GGLN EFVV KFYG PQGT PYEG GVWK VRVD LPDK YPFK SPSI GFMN KIFH PNID EASG TVCL DVIN QTWT ALYD LTNI FESF LPQL LAYP NPID PLNG DAAA MYLH RPEE YKQK IKEY IQKY ATEE ALKE QEEG TGDS SSES SMSD FSED EAQD MEL
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:GID3, UBC8, UBCH, UBCH2, E2-20K, UBE2H
Positive Sample:SW480, BT-474, 293T, U-251MG, SKOV3, Mouse thymus, Mouse liver, Mouse lung, Rat lung
Cellular Localization:Cytosol, Nucleus.
Calculated MW:21kDa
Observed MW:21-42kDa

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein sequence is 100% identical to the mouse homolog and 98% identical to the frog and zebrafish homologs. Three alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.

Purification MethodAffinity purification
Gene ID7328
RRIDAB_2767881
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using UBE2H Rabbit pAb (CAB7344) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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