Cell Cycle Antibodies 1

TRIOBP Rabbit Polyclonal Antibody (CAB4485)

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SKU:
CAB4485
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Cycle
Reactivity:
Human, Mouse
Synonyms:
TARA, TAP68, DFNB28, dJ37E16.4, HRIHFB2122, TRIOBP
Research Use:
Cell Cycle
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Description

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TRIOBP Antibody (CAB4485)

The TRIOBP Antibody (CAB4485) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for detecting TRIOBP in human samples and is validated for use in Western blot applications. By targeting the TRIOBP protein, researchers can analyze its expression and function in various cell types, providing insights into its role in auditory function and potential implications for hearing disorders.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:TRIOBP Antibody
SKU:CAB4485
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:DVTK LSDS NKEN ALHS YSTQ KGPL KAGE QRAG SEVI SRGG PRKA DGQR QALD YVEL SPLT QASP QRAR TPAR TPDR LAKQ EELE RDLA QRSE ERRK WFEA TDSR TPEV PAGE GPRR GLGA PLTE DQQN RLS
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:TARA, TAP68, DFNB28, dJ37E16.4, HRIHFB2122, TRIOBP
Positive Sample:BxPC-3, U-87MG, HeLa, LO2, A-549, SW620, Mouse liver
Cellular Localization:Cytoplasm, Midbody, Nucleus, Centrosome, Cytoskeleton, Cytoskeleton, Microtubule Organizing Center.
Calculated MW:261kDa
Observed MW:70kDa

This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).

Purification MethodAffinity purification
Gene ID11078
RRIDAB_2765707
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using TRIOBP Rabbit pAb (CAB4485) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 15s.
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