Cell Biology Antibodies 7

TMX1 Rabbit Polyclonal Antibody (CAB17219)

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SKU:
CAB17219
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Synonyms:
TMX, TXNDC, PDIA11, TXNDC1, TMX1
Research Use:
Cell Biology
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Description

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TMX1 Antibody (CAB17219)

The TMX1 Antibody (CAB17219) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the TMX1 protein, researchers can easily detect and analyze TMX1 expression in a variety of cell types, making it an ideal choice for studies related to protein folding, quality control, and endoplasmic reticulum stress.TMX1 is a key player in maintaining protein homeostasis and preventing the accumulation of misfolded proteins, which can lead to cellular dysfunction and disease.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:TMX1 Antibody
SKU:CAB17219
Size:20μL, 100μL
Reactivity:Human
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:KRRR PQPY PYPS KKLL SESA QPLK KVEE EQEA DEED VSEE EAES KEGT NKDF PQNA IRQR SLGP SLAT DKS
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:TMX, TXNDC, PDIA11, TXNDC1, TMX1
Positive Sample:293T, LO2, HeLa, Jurkat
Cellular Localization:Endoplasmic Reticulum Membrane, Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:32kDa
Observed MW:35kDa

This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides.

Purification MethodAffinity purification
Gene ID81542
RRIDAB_2772649
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using TMX1 Rabbit pAb (CAB17219) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
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