Cell Biology Antibodies 13

TMEM165 Rabbit Polyclonal Antibody (CAB17183)

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SKU:
CAB17183
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Synonyms:
FT27, GDT1, CDG2K, TPARL, TMPT27, SLC64A1, TMEM165
Research Use:
Cell Biology
Frequently bought together:

Description

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TMEM165 Antibody (CAB17183)

The TMEM165 Antibody (CAB17183) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit-derived antibody is highly specific for human samples and has been validated for use in Western blot and immunohistochemistry applications.TMEM165 plays a crucial role in maintaining calcium levels within cells and ensuring proper function of various organelles involved in cellular transport and signaling. Dysregulation of TMEM165 has been linked to diseases such as osteogenesis imperfecta and neurodegenerative disorders, making it an important target for research in the fields of cell biology and genetics.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:TMEM165 Antibody
SKU:CAB17183
Size:20μL, 100μL
Reactivity:Human
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:IRML REGL KMSP DEGQ EELE EVQA ELKK KDEE FQRT KLLN GPGD VETG TSIT VPQK KWL
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:FT27, GDT1, CDG2K, TPARL, TMPT27, SLC64A1, TMEM165
Positive Sample:HeLa
Cellular Localization:Golgi Apparatus.
Calculated MW:35kDa
Observed MW:35kDa

This gene encodes a predicted transmembrane protein with a perinuclear Golgi-like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation, type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID55858
RRIDAB_2772638
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from HeLa cells, using TMEM165 Rabbit pAb (CAB17183) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 5min.
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