Signal Transduction Antibodies 3

TCN2 Rabbit Polyclonal Antibody (CAB5755)

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SKU:
CAB5755
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
Reactivity:
Human, Mouse
Synonyms:
II, TC, TC2, TC-2, TCII, TC II, D22S676, D22S750, TCN2
Research Use:
Signal Transduction
Frequently bought together:

Description

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TCN2 Antibody (CAB5755)

The TCN2 Antibody (CAB5755) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced through immunization of rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting applications.Transcobalamin-2 plays a crucial role in vitamin B12 uptake and utilization, making it essential for various cellular processes including DNA synthesis and nerve function. Dysregulation of transcobalamin-2 has been linked to vitamin B12 deficiency and related health conditions, highlighting its importance in human health.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:TCN2 Antibody
SKU:CAB5755
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:EMCE IPEM DSHL VEKL GQHL LPWM DRLS LEHL NPSI YVGL RLSS LQAG TKED LYLH SLKL GYQQ CLLG SAFS EDDG DCQG KPSM GQLA LYLL ALRA NWHD HKGH PHTS YYQY GLGI LALC LHQK RVHD SVVD KLLY AVEP FHQG HHSV DTAA MAGL AFTC LKRS NFNP GRRQ RITM AIRT VREE ILKA QTPE GHFG NVYS TPLA LQFL MTSP MRGA ELGT ACLK ARVA LLAS
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:II, TC, TC2, TC-2, TCII, TC II, D22S676, D22S750, TCN2
Positive Sample:SW480, MCF7, A-549, U-251MG, Mouse kidney, Mouse lung
Cellular Localization:Secreted.
Calculated MW:48kDa
Observed MW:54kDa

This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID6948
RRIDAB_2766509
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using TCN2 Rabbit pAb (CAB5755) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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