Cell Death Antibodies 1

STEAP3 Rabbit Polyclonal Antibody (CAB0683)

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SKU:
CAB0683
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
Reactivity:
Human, Mouse
Synonyms:
STMP3, TSAP6, pHyde, AHMIO2, dudlin-2, dudulin-2, STEAP3
Research Use:
Cell Death
Frequently bought together:

Description

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STEAP3 Antibody (CAB0683)

The STEAP3 Antibody (CAB0683) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in various applications such as Western blotting. By targeting the STEAP3 protein, researchers can gain insights into its role in cellular processes and potential implications in cancer and other diseases.STEAP3 is a metalloreductase enzyme that plays a critical role in cellular iron metabolism and redox balance. Dysregulation of STEAP3 has been associated with various cancers, making it a potential target for cancer therapies.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:STEAP3 Antibody
SKU:CAB0683
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MPEE MDKP LISL HLVD SDSS LAKV PDEA PKVG ILGS GDFA RSLA TRLV GSGF KVVV GSRN PKRT ARLF PSAA QVTF QEEA VSSP EVIF VAVF REHY SSLC SLSD QLAG KILV DVSN PTEQ EHLQ HRES NAEY LASL FPTC TVVK AFNV ISAW TLQA GPRD GNRQ VPIC GDQP EAKR AVSE
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:STMP3, TSAP6, pHyde, AHMIO2, dudlin-2, dudulin-2, STEAP3
Positive Sample:Mouse heart
Cellular Localization:Endosome Membrane, Multi-Pass Membrane Protein.
Calculated MW:55kDa
Observed MW:55kDa

This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID55240
RRIDAB_2757334
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from mouse heart, using STEAP3 Rabbit pAb (CAB0683) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 60s.
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