Signal Transduction Antibodies 3

STAMBP Rabbit Polyclonal Antibody (CAB7065)

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SKU:
CAB7065
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
Reactivity:
Human, Mouse, Rat
Synonyms:
AMSH, MICCAP, STAMBP
Research Use:
Signal Transduction
Frequently bought together:

Description

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STAMBP Antibody (CAB7065)

The STAMBP Antibody (CAB7065) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is produced by immunizing rabbits and is highly reactive with human samples, making it suitable for a variety of experimental applications.STAMBP is a critical regulator of endosomal sorting and recycling, playing a key role in maintaining cellular homeostasis and proper functioning of the endocytic pathway.

This antibody is validated for use in WB, IHC-P, IF/ICC, IP, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:STAMBP Antibody
SKU:CAB7065
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:FPKA EELK AELL KRYT KEYT EYNE EKKK EAEE LARN MAIQ QELE KEKQ RVAQ QKQQ QLEQ EQFH AFEE MIRN QELE KERL KIVQ EFGK VDPG LGGP LVPD LEKP SLDV FPTL TVSS IQPS DCHT TVRP AKPP VVDR SLKP GALS NSES IPTI DGLR HVVV PGRL CPQF LQL
Tested Applications:WB IHC-P IF/ICC IP ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
IF/ICC1:50 - 1:100
IP0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:AMSH, MICCAP, STAMBP
Positive Sample:MCF7, SW480, HepG2, HeLa, 293T, Mouse brain, Rat lung, Rat liver
Cellular Localization:Cytoplasm, Early Endosome, Membrane, Nucleus, Peripheral Membrane Protein.
Calculated MW:48kDa
Observed MW:48kDa

Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

Purification MethodAffinity purification
Gene ID10617
RRIDAB_2767620
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using STAMBP Rabbit pAb (CAB7065) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat spleen using STAMBP Rabbit pAb (CAB7065) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
Product ImageImmunofluorescence analysis of U2OS cells using STAMBP Rabbit pAb (CAB7065). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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