Cell Biology Antibodies 10

SRI Rabbit Polyclonal Antibody (CAB6751)

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SKU:
CAB6751
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
SCN, V19, CP22, CP-22, RI
Research Use:
Cell Biology
Frequently bought together:

Description

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SRI Antibody (CAB6751)

The SRI Antibody (CAB6751) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot and immunohistochemistry applications.Sorcin, also known as Soluble Resistance-Related Calcium Binding Protein, is involved in regulating calcium homeostasis and has been implicated in drug resistance in cancer cells. Its expression has been linked to various cancer types, making it a promising target for cancer research and drug development.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:SRI Antibody
SKU:CAB6751
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MAYP GHPG AGGG YYPG GYGG APGG PAFP GQTQ DPLY GYFA AVAG QDGQ IDAD ELQR CLTQ SGIA GGYK PFNL ETCR LMVS MLDR DMSG TMGF NEFK ELWA VLNG WRQH FISF DTDR SGTV DPQE LQKA LTTM GFRL SPQA VNSI AKRY STNG KITF DDYI ACCV KLRA LTDS FRRR DTAQ QGVV NFPY DDFI QCVM SV
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:100
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:SCN, V19, CP22, CP-22, RI
Positive Sample:HeLa
Cellular Localization:Cytoplasm, Cytoplasmic Side, Peripheral Membrane Protein, Sarcoplasmic Reticulum Membrane.
Calculated MW:22kDa
Observed MW:20kDa

This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene.

Purification MethodAffinity purification
Gene ID6717
RRIDAB_2767335
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from wild type(WT) and SRI knockout (KO) HeLa(KO) cells, using [KO Validated] SRI Rabbit pAb (CAB6751) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human liver damage using [KO Validated] SRI Rabbit pAb (CAB6751) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Mouse heart using [KO Validated] SRI Rabbit pAb (CAB6751) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
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