Epigenetics & Nuclear Signaling Antibodies 2

SOX10 Rabbit Polyclonal Antibody (CAB15100)

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SKU:
CAB15100
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse, Rat
Synonyms:
DOM, WS4, PCWH, WS2E, WS4C, SOX-10, SOX10
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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SOX10 Antibody (CAB15100)

The SOX10 Antibody (CAB15100) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an excellent choice for Western blot applications.SOX10 is known for its role in the regulation of genes essential for the differentiation of melanocytes, Schwann cells, and oligodendrocytes. Dysregulation of SOX10 has been implicated in various diseases, including neurocristopathies and certain types of cancer.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:SOX10 Antibody
SKU:CAB15100
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:HIDF GNVD IGEI SHEV MSNM ETFD VAEL DQYL PPNG HPGH VSSY SAAG YGLG SALA VASG HSAW ISKP PGVA LPTV SPPG VDAK AQVK TET
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:200
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:DOM, WS4, PCWH, WS2E, WS4C, SOX-10, SOX10
Positive Sample:SK-MEL-28, Neuro-2a
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:50kDa
Observed MW:62kDa

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

Purification MethodAffinity purification
Gene ID6663
RRIDAB_2761984
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using SOX10 Rabbit pAb (CAB15100) at 1:600 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates / proteins: 25 μg per lane. Blocking buffer: 3 % nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 20s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat brain using SOX10 Rabbit pAb (CAB15100) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
Product ImageImmunofluorescence analysis of C6 cells using SOX10 Rabbit pAb (CAB15100) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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