Cell Biology Antibodies 5

RNASEH2A Rabbit Polyclonal Antibody (CAB15132)

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SKU:
CAB15132
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Rat
Synonyms:
AGS4, JUNB, RNHL, RNHIA, THSD8, RNASEHI, RNASEH2A
Research Use:
Cell Biology
Frequently bought together:

Description

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RNASEH2A Antibody (CAB15132)

The RNASEH2A Antibody (CAB15132) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the RNASEH2A protein, researchers can effectively detect and analyze its expression in various cell types, making it a key asset for studies in molecular biology and genetics.RNASEH2A is a critical enzyme that plays a crucial role in maintaining genomic stability by removing RNA fragments from DNA.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Rat samples.

Product Name:RNASEH2A Antibody
SKU:CAB15132
Size:20μL, 100μL
Reactivity:Human, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MDLS ELER DNTG RCRL SSPV PAVC RKEP CVLG VDEA GRGP VLGP MVYA ICYC PLPR LADL EALK VADS KTLL ESER ERLF AKME DTDF VGWA LDVL SPNL ISTS MLGR VKYN LNSL SHDT ATGL IQYA LDQG VNVT QVFV DTVG MPET YQAR LQQS FPGI EVTV KAKA DALY PVVS AASI CAKV ARDQ AVKK WQFV EKLQ DLDT DYGS GYPN DPKT KAWL KEHV EPVF GFPQ FVRF SWRT AQTI LEKE AEDV IWED SASE NQEG LRKI TSYF LNEG SQAR PRSS HRYF LERG LESA TSL
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:AGS4, JUNB, RNHL, RNHIA, THSD8, RNASEHI, RNASEH2A
Positive Sample:rat ovary, rat testis, rat liver
Cellular Localization:Nucleus.
Calculated MW:33kDa
Observed MW:33kDa

The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.

Purification MethodAffinity purification
Gene ID10535
RRIDAB_2762018
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using RNASEH2A Rabbit pAb (CAB15132) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Product ImageImmunofluorescence analysis of C6 cells using RNASEH2A Rabbit pAb (CAB15132) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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