Epigenetics & Nuclear Signaling Antibodies 1

PRPS2 Rabbit Polyclonal Antibody (CAB12644)

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SKU:
CAB12644
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse, Rat
Synonyms:
PRSII, PRPS2
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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PRPS2 Antibody (CAB12644)

The PRPS2 Antibody (CAB12644) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific for human PRPS2 and has been validated for use in Western blotting applications.PRPS2 plays a crucial role in maintaining nucleotide pools for DNA and RNA synthesis, making it essential for cell proliferation and growth. Dysregulation of PRPS2 has been implicated in various diseases, including cancer and metabolic disorders.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:PRPS2 Antibody
SKU:CAB12644
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MPNI VLFS GSSH QDLS QRVA DRLG LELG KVVT KKFS NQET SVEI GESV RGED VYII QSGC GEIN DNLM ELLI MINA CKIA SSSR VTAV IPCF PYAR QDKK DKSR APIS AKLV ANML SVAG ADHI ITMD LHAS QIQG FFDI PVDN LYAE PAVL QWIR ENIA EWKN CIIV SPDA GGAK RVTS IADR LNVE FALI HKER KKAN EVDR MVLV GDVK DRVA ILVD DMAD TCGT ICHA ADKL LSAG
Tested Applications:WB ELISA
Recommended Dilution:
WB1:1000 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PRSII, PRPS2
Positive Sample:HeLa, MCF7, Mouse brain, Mouse heart, Mouse kidney, Rat liver
Cellular Localization:Cytoplasm, Cytosol.
Calculated MW:35kDa
Observed MW:35kDa

This gene encodes a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID5634
RRIDAB_2759489
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using PRPS2 Rabbit pAb (CAB12644) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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