Epigenetics & Nuclear Signaling Antibodies 5

Reptin/RUVBL2 Rabbit Monoclonal Antibody (CAB4227)

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SKU:
CAB4227
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
Antibody Type:
Monoclonal Antibody
Synonyms:
RVB2, TIH2, ECP51, TIP48, CGI-46, ECP-51, INO80J, REPTIN, TIP49B, TAP54-beta, Reptin/RUVBL2
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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Reptin/RUVBL2 Monoclonal Antibody (CAB4227)

The Reptin/RUVBL2 Monoclonal Antibody (CAB4227) is a high-quality antibody developed for reliable detection and analysis of target proteins. This highly specific antibody, developed using rabbit monoclonal technology, offers exceptional reactivity with human samples and is validated for use in Western blot applications.The Reptin/RuvBL2 protein, also known as Pontin or TIP49, is a key component of many protein complexes involved in regulating gene expression and maintaining genomic stability. Its involvement in essential cellular functions makes it a promising target for research in fields such as cancer biology, cell biology, and genomics.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.

Product Name:Reptin/RUVBL2 Monoclonal Antibody
SKU:CAB4227
Size:20μL, 100μL
Reactivity:Mouse
Clone Number:ARC0933
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:LLDR LLIV STTP YSEK DTKQ ILRI RCEE EDVE MSED AYTV LTRI GLET SLRY AIQL ITAA SLVC RKRK GTEV QVDD IKRV YSLF LDES RSTQ YMKE YQDA F
Tested Applications:WB ELISA
Recommended Dilution:
WB1:1000 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:RVB2, TIH2, ECP51, TIP48, CGI-46, ECP-51, INO80J, REPTIN, TIP49B, TAP54-beta, Reptin/RUVBL2
Positive Sample:Mouse testis, Mouse thymus
Cellular Localization:Cytoplasm, Membrane, Nucleus, Nucleus Matrix, Nucleoplasm.
Calculated MW:51kDa
Observed MW:50kDa

This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.

Purification MethodAffinity purification
Gene ID10856
RRIDAB_2863214
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using Reptin/RUVBL2 Rabbit mAb (CAB4227) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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