Cell Biology Antibodies 11

PKC gamma Rabbit Polyclonal Antibody (CAB7922)

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SKU:
CAB7922
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
PKCC, PKCG, SCA14, PKCI(3), PKCgamma, PKC-gamma, PKC gamma
Research Use:
Cell Biology
Frequently bought together:

Description

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PKC gamma Antibody (CAB7922)

The PKC gamma Antibody (CAB7922) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PRKCG protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and cancer research.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:PKC gamma Antibody
SKU:CAB7922
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:EDEE ELFQ AIME QTVT YPKS LSRE AVAI CKGF LTKH PGKR LGSG PDGE PTIR AHGF FRWI DWER LERL EIPP PFRP RPCG RSGE NFDK FFTR AAPA LTPP DRLV LASI DQAD FQGF TYVN PDFV HPDA RSPT SPVP VPVM
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PKCC, PKCG, SCA14, PKCI(3), PKCgamma, PKC-gamma, PKC gamma
Positive Sample:THP-1, Rat brain
Cellular Localization:Cell Junction, Cell Membrane, Cell Projection, Cytoplasm, Peripheral Membrane Protein, Dendrite, Perinuclear Region, Synapse, Synaptosome.
Calculated MW:78kDa
Observed MW:78kDa

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). Two transcript variants encoding different isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID5582
RRIDAB_2771828
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using PKC gamma Rabbit pAb (CAB7922) at 1:500 dilution._Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Basic Kit (AbGn00020)._Exposure time: 90s.
Product ImageWestern blot analysis of various lysates using PKC gamma Rabbit pAb (CAB7922) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
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