Cell Biology Antibodies 15

PPP2R1A/PPP2R2A/PPP2R1B Rabbit Polyclonal Antibody (CAB18571)

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SKU:
CAB18571
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
PPP2R1A/PPP2R2A/PPP2R1B
Research Use:
Cell Biology
Frequently bought together:

Description

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PPP2R1A/PPP2R2A/PPP2R1B Antibody (CAB18571)

The PPP2R1A/PPP2R2A/PPP2R1B Antibody (CAB18571) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, demonstrates high reactivity with human samples and is ideal for use in Western blot applications. By binding to the PPP2R1A, PPP2R2A, and PPP2R1B proteins, this antibody enables accurate detection and analysis in various cell types, making it essential for studies in cell signaling, cancer research, and developmental biology.PP2A is a crucial serine/threonine phosphatase involved in regulating a wide range of cellular processes, including cell growth, division, and apoptosis.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:PPP2R1A/PPP2R2A/PPP2R1B Antibody
SKU:CAB18571
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MAAA DGDD SLYP IAVL IDEL RNED VQLR LNSI KKLS TIAL ALGV ERTR SELL PFLT DTIY DEDE VLLA LAEQ LGTF TTLV GGPE YVHC LLPP LESL ATVE ETVV RDKA VESL RAIS HEHS PSDL EAHF VPLV KRLA GGDW FTSR TSAC GLFS VCYP RVSS A
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PPP2R1A/PPP2R2A/PPP2R1B
Positive Sample:HeLa, HepG2, K-562, NIH/3T3, C6, Mouse liver, Mouse lung, Rat brain, Rat testis
Cellular Localization:Cytoplasm, Cytosol, Dendrite, Extracellular Exosome, Glutamatergic Synapse, Lateral Plasma Membrane, Microtubule Cytoskeleton, Mitochondrion, Neuron Projection, Nucleus.
Observed MW:55kDa/66kDa

Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.The B regulatory subunit might modulate substrate selectivity and catalytic activity.

Purification MethodAffinity purification
Gene ID5518 5520 5519
RRIDAB_2862335
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using PPP2R1A/PPP2R2A/PPP2R1B Rabbit pAb (CAB18571) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
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