Cell Biology Antibodies 10

PLEK Rabbit Polyclonal Antibody (CAB6305)

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SKU:
CAB6305
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
P47, PLEK1, PLEK
Research Use:
Cell Biology
Frequently bought together:

Description

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PLEK Antibody (CAB6305)

The PLEK Antibody (CAB6305) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from rabbit serum, exhibits high specificity and sensitivity towards human pleckstrin, making it ideal for use in Western blotting and immunohistochemistry applications.Pleckstrin is involved in a variety of cellular processes, including cell proliferation, differentiation, and apoptosis. Dysregulation of pleckstrin has been linked to various diseases, such as cancer and neurological disorders, highlighting the importance of studying its function and regulation.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:PLEK Antibody
SKU:CAB6305
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MEPK RIRE GYLV KKGS VFNT WKPM WVVL LEDG IEFY KKKS DNSP KGMI PLKG STLT SPCQ DFGK RMFV FKIT TTKQ QDHF FQAA FLEE RDAW VRDI KKAI KCIE GGQK FARK STRR SIRL PETI DLGA LYLS MKDT EKGI KELN LEKD KKIF NHCF TGNC VIDW LVSN QSVR NRQE GLMI ASSL LNEG YLQP AGDM SKSA VDGT AENP FLDN PDAF YYFP DSGF FCEE NSSD DDVI LKEE FRGV IIKQ GCLL KQGH RRKN WKVR KFIL REDP AYLH YYDP AGAE DPLG AIHL RGCV VTSV ESNS NGRK SEEE NLFE IITA DEVH YFLQ AATP KERT EWIR AIQM ASRT GK
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:P47, PLEK1, PLEK
Positive Sample:THP-1, U-937, Mouse lung, Mouse spleen, Rat spleen
Cellular Localization:Cytoplasm, Cytosol, Extracellular Region, Plasma Membrane, Ruffle Membrane.
Calculated MW:40kDa
Observed MW:40kDa

Enables phosphatidylinositol-3,4-bisphosphate binding activity; protein homodimerization activity; and protein kinase C binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; actin cytoskeleton organization; and positive regulation of supramolecular fiber organization. Located in cytoplasm and ruffle membrane.

Purification MethodAffinity purification
Gene ID5341
RRIDAB_2766910
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using PLEK Rabbit pAb (CAB6305) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
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