Cell Biology Antibodies 10

Pannexin 1 Rabbit Polyclonal Antibody (CAB6683)

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SKU:
CAB6683
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse
Synonyms:
PX1, MRS1, OOMD7, OZEMA7, UNQ2529, Pannexin 1
Research Use:
Cell Biology
Frequently bought together:

Description

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Pannexin 1 Antibody (CAB6683)

The Pannexin 1 Antibody (CAB6683) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to pannexin-1, this antibody allows for the detection and analysis of this important protein in a variety of cell types, making it an invaluable resource for studies in cell biology and neuroscience.Pannexin-1 is known to play a crucial role in mediating various cellular functions, including the release of ATP and other signaling molecules.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:Pannexin 1 Antibody
SKU:CAB6683
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:ISLA FAQE ISIG TQIS CFSP SSFS WRQA AFVD SYCW AAVQ QKNS LQSE SGNL PLWL HKFF PYIL LLFA ILLY LPPL FWRF AAAP HICS DLKF IMEE LDKV Y
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PX1, MRS1, OOMD7, OZEMA7, UNQ2529, Pannexin 1
Positive Sample:DU145, HeLa, MCF7, Mouse skin, Mouse spleen, Mouse brain
Cellular Localization:Cell Junction, Cell Membrane, Endoplasmic Reticulum Membrane, Multi-Pass Membrane Protein, Multi-Pass Membrane Protein, Gap Junction.
Calculated MW:48kDa
Observed MW:54kDa

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.

Purification MethodAffinity purification
Gene ID24145
RRIDAB_2767267
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using Pannexin 1 Rabbit pAb (CAB6683) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 15s.
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