Cell Biology Antibodies 1

PADI1 Rabbit Polyclonal Antibody (CAB10145)

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SKU:
CAB10145
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Mouse, Rat
Synonyms:
PDI, PAD1, PDI1, HPAD10, PADI1
Research Use:
Cell Biology
Frequently bought together:

Description

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PADI1 Antibody (CAB10145)

The PADI1 Antibody (CAB10145) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting PADI1 in human samples, making it a reliable tool for immunohistochemistry and immunofluorescence experiments.PADI1 plays a crucial role in various biological processes, including gene regulation, chromatin remodeling, and immune responses. Dysregulation of PADI1 has been implicated in autoimmune diseases, inflammatory disorders, and cancer development.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.

Product Name:PADI1 Antibody
SKU:CAB10145
Size:20μL, 100μL
Reactivity:Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MAPK RVVQ LSLK MPTH AVCV VGVE AHVD IHSD VPKG ANSF RVSG SSGV EVFM VYNR TRVK EPIG KARW PLDT DADM VVSV GTAS KELK DFKV RVSY FGEQ EDQA LGRS VLYL TGVD ISLE VDTG RTGK VKRS QGDK KTWR WGPE GYGA ILLV NCDR DNHR SAEP DLTH SWLM SLAD LQDM SPML LSCN GPDK LFDS HKLV LNVP FSDS KRVR VFCA RGGN SLSD YKQV LGPQ CLSY EVER QPGE QEIK FYVE GLTF PDAD FLGL VSLS VSLV DPGT L
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PDI, PAD1, PDI1, HPAD10, PADI1
Positive Sample:Mouse ovary, Rat uterus
Cellular Localization:Cytoplasm.
Calculated MW:75kDa
Observed MW:75kDa

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes.

Purification MethodAffinity purification
Gene ID29943
RRIDAB_2757672
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates, using PADI1 Rabbit pAb (CAB10145) at 1:600 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
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