Cell Biology Antibodies 8

Purinergic Receptor P2Y6 Rabbit Polyclonal Antibody (CAB2485)

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SKU:
CAB2485
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse
Synonyms:
P2Y6, Purinergic Receptor P2Y6
Research Use:
Cell Biology
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Description

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Purinergic Receptor P2Y6 Antibody (CAB2485)

The Purinergic Receptor P2Y6 Antibody (CAB2485) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, specifically targets the P2Y purinoceptor 6 protein and is highly reactive with human samples. Validated for use in Western blot applications, the antibody allows for the detection and analysis of P2Y purinoceptor 6 in various cell types.P2Y purinoceptor 6 is a G protein-coupled receptor that responds to extracellular nucleotides, playing a crucial role in processes such as platelet aggregation, inflammation, and neurotransmission.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:Purinergic Receptor P2Y6 Antibody
SKU:CAB2485
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:GFLL PFAA LLAC YCLL ACRL CRQD GPAE PVAQ ERRG KAAR MAVV VAAA FAIS FLPF HITK TAYL AVRS TPGV PCTV LEAF AAAY KGTR PFAS ANSV LDPI L
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:P2Y6, Purinergic Receptor P2Y6
Positive Sample:Mouse lung
Cellular Localization:Cell Membrane, Multi-Pass Membrane Protein.
Calculated MW:36kDa
Observed MW:42kDa

The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Purification MethodAffinity purification
Gene ID5031
RRIDAB_2764377
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Mouse lung, using Purinergic Receptor P2Y6 Rabbit pAb (CAB2485) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
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