Epigenetics & Nuclear Signaling Antibodies 1

Progesterone Receptor Rabbit Polyclonal Antibody (CAB0321)

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SKU:
CAB0321
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse, Rat
Synonyms:
PR, NR3C3, Progesterone Receptor
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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Progesterone Receptor Antibody (CAB0321)

The Progesterone Receptor Antibody (CAB0321) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically targets the PGR protein, enabling accurate detection and analysis in a variety of cell types.The progesterone receptor plays a crucial role in mediating the effects of progesterone in the female reproductive system, influencing processes such as ovulation, implantation, and pregnancy maintenance. Dysregulation of PGR signaling has been implicated in various reproductive disorders, including infertility, endometriosis, and certain types of cancer.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:Progesterone Receptor Antibody
SKU:CAB0321
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MTEL KAKG PRAP HVAG GPPS PEVG SPLL CRPA AGPF PGSQ TSDT LPEV SAIP ISLD GLLF PRPC QGQD PSDE KTQD QQSL SDVE GAYS RAEA TRGA GGSS SSPP EKDS GLLD SVLD TLLA PSGP GQSQ PSPP ACEV TSSW CLFG PELP EDPP AAPA TQRV LSPL MSRS GCKV GDSS GTAA AHKV LPRG LSPA RQLL LPAS ESPH WSGA PVKP SPQA AAVE VEEE DGSE SEES AGPL LKGK PRAL GGAA AG
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PR, NR3C3, Progesterone Receptor
Positive Sample:BT-474, Mouse brain, Rat brain
Cellular Localization:Cytoplasm, Cytoplasm, Mitochondrion Outer Membrane, Nucleus.
Calculated MW:99kDa
Observed MW:118kDa

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.

Purification MethodAffinity purification
Gene ID5241
RRIDAB_2757125
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Progesterone Receptor Rabbit pAb (CAB0321) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat fallopian tube using Progesterone Receptor Rabbit pAb (CAB0321) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Mouse uterus using Progesterone Receptor Rabbit pAb (CAB0321) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
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