Developmental Biology

Oncostatin M Rabbit Polyclonal Antibody (CAB6163)

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SKU:
CAB6163
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
OSM, Oncostatin M
Research Use:
Developmental Biology
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Description

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Oncostatin M Antibody (CAB6163)

The Oncostatin M Antibody (CAB6163) is a high-quality antibody developed for reliable detection and analysis of target proteins. Oncostatin M is a cytokine that plays a key role in various physiological processes, including cell growth, differentiation, and immune response modulation.This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It binds specifically to the Oncostatin M protein, allowing for precise detection and analysis in a variety of cell types.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:Oncostatin M Antibody
SKU:CAB6163
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:AAIG SCSK EYRV LLGQ LQKQ TDLM QDTS RLLD PYIR IQGL DVPK LREH CRER PGAF PSEE TLRG LGRR GFLQ TLNA TLGC VLHR LADL EQRL PKAQ DLER SGLN IEDL EKLQ MARP NILG LRNN IYCM AQLL DNSD TAEP TKAG RGAS QPPT PTPA SDAF QRKL EGCR FLHG YHRF MHSV GRVF SKWG ESPN RSRR HSPH QALR KGVR RTRP SRKG KRLM TRGQ LPR
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:OSM, Oncostatin M
Positive Sample:HepG2, NIH/3T3, Mouse uterus, Mouse heart
Cellular Localization:Secreted.
Calculated MW:28kDa
Observed MW:28kDa

This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Purification MethodAffinity purification
Gene ID5008
RRIDAB_2766790
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using Oncostatin M Rabbit pAb (CAB6163) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 60s.
Product ImageImmunofluorescence analysis of C6 cells using Oncostatin M Rabbit pAb (CAB6163) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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