NR1D2 Rabbit Polyclonal Antibody (CAB20447)

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SKU:
CAB20447
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Host Species:
Rabbit
Isotype:
IgG
Reactivity:
Mouse, Rat
Synonyms:
RVR, BD73, EAR-1R, REVERBB, REVERBbeta, Rev-erb beta/NR1D2
Frequently bought together:

Description

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NR1D2 Antibody (CAB20447)

The NR1D2 Antibody (CAB20447) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity for human samples and is validated for use in Western blotting applications. By targeting the NR1D2 protein, this antibody allows for the visualization and analysis of NR1D2 expression in a variety of cell types, making it an essential component of studies in chronobiology and metabolic research.NR1D2, also known as Rev-erb alpha, is a key regulator of the circadian clock and metabolic pathways, influencing processes such as energy metabolism, lipid homeostasis, and glucose regulation.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.

Product Name:NR1D2 Antibody
SKU:CAB20447
Size:20μL, 100μL
Reactivity:Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:ALPA QEQL RPKP QLEQ ENIK SSSP PSSD FAKE EVIG MVTR AHKD TFMY NQEQ QENS AESM QPQR GERI PKNM EQYN LNHD H
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:RVR, BD73, EAR-1R, REVERBB, REVERBbeta, Rev-erb beta/NR1D2
Positive Sample:Mouse lung, Mouse brain, Mouse skeletal muscle, Rat lung, Rat skeletal muscle, Rat heart
Cellular Localization:Cytoplasm, Nucleoplasm, Nucleus.
Calculated MW:65kDa
Observed MW:70kDa

This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.

Purification MethodAffinity purification
Gene ID9975
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using Rev-erb beta/NR1D2 Rabbit pAb (CAB20447) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
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