Cell Biology Antibodies 6

NECAB3 Rabbit Polyclonal Antibody (CAB15500)

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SKU:
CAB15500
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
NIP1, XB51, STIP3, EFCBP3, SYTIP2, APBA2BP, dJ63M2.4, dJ63M2.5, NECAB3
Research Use:
Cell Biology
Frequently bought together:

Description

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NECAB3 Antibody (CAB15500)

The NECAB3 Antibody (CAB15500) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting NECAB3 in human samples, making it suitable for use in various research applications such as Western blotting.NECAB3 is known to play a crucial role in regulating synaptic transmission and plasticity in the brain, making it a promising target for studies on neurological disorders and neurodegenerative diseases.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:NECAB3 Antibody
SKU:CAB15500
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MACA GLLT VCLL RPPA PQPQ PQTP RHPQ LAPD PGPA GHTL FQDV FRRA DKND DGKL SFEE FQNY FADG VLSL GELQ ELFS GIDG HLTD NLET EKLC DYFS EHLG VYRP VLAA LESL NRAV LAAM DATK LEYE RASK VDQF VTRF LLRE TVSQ LQAL QSSL EGAS DTLE AQAH GWRS DAES VEAQ SRLC GSRR AGRR ALRS VSRS STWS PGSS DTGR SSEA EMQW RLQV NRLQ ELID QLEC KAPR LEPL REED LAKG PDLH ILMA QRQV QVAE EGLQ DFHR ALRC YVDF TGAQ SHCL HVSA QKML DGAS FTLY EFWQ DEAS WRRH QQSP GSKA FQRI LIDH LRAP DTLT TVFF PASW WIMN NN
Tested Applications:WB ELISA
Recommended Dilution:
WB1:200 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:NIP1, XB51, STIP3, EFCBP3, SYTIP2, APBA2BP, dJ63M2.4, dJ63M2.5, NECAB3
Positive Sample:LO2, Mouse liver, Rat liver
Cellular Localization:Golgi Apparatus.
Calculated MW:44kDa
Observed MW:50kDa

The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID63941
RRIDAB_2762900
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using NECAB3 Rabbit pAb (CAB15500) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
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