Epigenetics & Nuclear Signaling Antibodies 4

NCOR2 Rabbit Polyclonal Antibody (CAB8388)

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SKU:
CAB8388
Product Type:
Antibody
Applications:
WB
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
SMRT, TRAC, CTG26, SMRTE, TRAC1, N-CoR2, TNRC14, TRAC-1, SMAP270, SMRTE-tau, NCOR2
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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NCOR2 Antibody (CAB8388)

The NCOR2 Antibody (CAB8388) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot assays. By binding specifically to NCOR2, this antibody facilitates the detection and exploration of NCOR2 protein levels in various cell types, making it an invaluable resource for investigations in molecular biology and cancer research.NCOR2, also known as nuclear receptor corepressor 2, plays a key role in mediating transcriptional repression and influencing diverse biological processes, including cell growth and differentiation.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:NCOR2 Antibody
SKU:CAB8388
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MSGS TQPV AQTW RATE PRYP PHSL SYPV QIAR THTD VGLL EYQH HSRD YASH LSPG SIIQ PQRR RPSL LSEF QPGN ERSQ ELHL RPES HSYL PELG KSEM EFIE SKRP RLEL L
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:SMRT, TRAC, CTG26, SMRTE, TRAC1, N-CoR2, TNRC14, TRAC-1, SMAP270, SMRTE-tau, NCOR2
Positive Sample:HeLa, LO2
Cellular Localization:Nucleus.
Calculated MW:274kDa
Observed MW:275kDa

This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.

Purification MethodAffinity purification
Gene ID9612
RRIDAB_2770536
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using NCOR2 Rabbit pAb (CAB8388) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020).
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat spleen using NCOR2 Rabbit pAb (CAB8388) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Mouse brain using NCOR2 Rabbit pAb (CAB8388) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
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