Cell Biology Antibodies 17

MRPS18C Rabbit Polyclonal Antibody (CAB18453)

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SKU:
CAB18453
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
CGI-134, S18mt-c, MRPS18-1, mrps18-c, MRP-S18-1, MRP-S18-c, MRPS18C
Research Use:
Cell Biology
Frequently bought together:

Description

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MRPS18C Antibody (CAB18453)

The MRPS18C Antibody (CAB18453) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples and has been validated for use in Western blot applications. By targeting the MRPS18C protein, researchers can investigate its role in mitochondrial function and its implications in various cellular processes.MRPS18C is a key component of the mitochondrial ribosome, where it assists in the translation of mitochondrial DNA into functional proteins necessary for energy production.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:MRPS18C Antibody
SKU:CAB18453
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MAAV VAVC GGLG RKKL THLV TAAV SLTH PGTH TVLW RRGC SQQV SSNE DLPI SMEN PYKE PLKK CILC GKHV DYKN VQLL SQFV SPFT GCIY GRHI TGLC GKKQ KEIT KAIK RAQI MGFM PVTY KDPA YLKD PKVC NIRY RE
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CGI-134, S18mt-c, MRPS18-1, mrps18-c, MRP-S18-1, MRP-S18-c, MRPS18C
Positive Sample:U-87MG, HepG2, 293T
Cellular Localization:Mitochondrial Inner Membrane.
Calculated MW:16kDa
Observed MW:15kDa

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q.

Purification MethodAffinity purification
Gene ID51023
RRIDAB_2862220
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using MRPS18C Rabbit pAb (CAB18453) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
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