Cell Biology Antibodies 12

Mannose Receptor/CD206 Polyclonal Antibody (CAB8301)

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SKU:
CAB8301
Product Type:
Antibody
Applications:
WB
Applications:
IHC
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Mouse, Rat
Synonyms:
MMR, hMR, CD206, MRC1L1, CLEC13D, CLEC13DL, bA541I19.1, Mannose Receptor/CD206
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

Mannose Receptor/CD206 Polyclonal Antibody (CAB8301)

The Mannose Receptor/CD206 Polyclonal Antibody (CAB8301) is a high-quality antibody developed for reliable detection and analysis of target proteins. This cell surface receptor plays a crucial role in the immune system, specifically in the recognition and clearance of pathogens and foreign molecules. Raised in rabbits, this antibody is highly specific for human samples and has been validated for use in Western blot applications. It binds to the MRC1 protein, enabling researchers to detect and analyze its expression in various cell types. This makes it an ideal tool for studies in immunology, infectious diseases, and cancer research.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.

Product Name:Mannose Receptor/CD206 Polyclonal Antibody
SKU:CAB8301
Size:20μL, 100μL
Reactivity:Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:GLWD VLKC DEKA KFVC KHWA EGVT HPPK PTTT PEPK CPED WGAS SRTS LCFK LYAK GKHE KKTW FESR DFCR ALGG DLAS INNK EEQQ TIWR LITA SGSY HKLF WLGL TYGS PSEG FTWS DGSP VSYE NWAY GEPN NYQN VEYC GELK GDPT MSWN DINC EHLN NWIC QIQK GQTP KPEP TPAP QDNP PVTE DGWV IYKD YQYY FSKE KETM DNAR AFCK RNFG DLVS IQSE SEKK FLWK YVNR NDAQ SAY
Tested Applications:WB ELISA
Recommended Dilution:
WB1:1000 - 1:5000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:MMR, hMR, CD206, MRC1L1, CLEC13D, CLEC13DL, bA541I19.1, Mannose Receptor/CD206
Positive Sample:Rat lung
Cellular Localization:Cell Membrane, Endosome Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:166kDa
Observed MW:190-250kDa

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.

Purification MethodAffinity purification
Gene ID4360
RRIDAB_2770422
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using Mannose Receptor/CD206 Rabbit pAb (CAB8301) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Negative control (NC): Jurkat. Exposure time: 30s.
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