Cell Biology Antibodies 18

MOB1A/MOB1B Rabbit Polyclonal Antibody (CAB18246)

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SKU:
CAB18246
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
MOB1A/MOB1B
Research Use:
Cell Biology
Frequently bought together:

Description

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MOB1A/MOB1B Antibody (CAB18246)

The MOB1A/MOB1B Antibody (CAB18246) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications.MOB1A and MOB1B are essential components of the Hippo signaling pathway, which controls organ size and tissue homeostasis. Dysregulation of this pathway has been implicated in various diseases, including cancer.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:MOB1A/MOB1B Antibody
SKU:CAB18246
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:TILK RLFR VYAH IYHQ HFDS VMQL QEEA HLNT SFKH FIFF VQEF NLID RREL APLQ ELIE KLGS KDR/ MSFL FGSR SSKT FKPK KNIP EGSH QYEL LKHA E
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:MOB1A/MOB1B
Positive Sample:K-562, Daudi, NIH/3T3, C6, C2C12
Cellular Localization:Cytoplasm, Cytosol, Extracellular Exosome, Nucleolus, Nucleoplasm, Nucleus.
Observed MW:24kDa

The protein MOB1 is considered to be one of the core components of the mammalian Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. MOB1A and MOB1B, which have 95% sequence identity, play redundant biological roles and are both termed MOB1.

Purification MethodAffinity purification
Gene ID55233 92597
RRIDAB_2862022
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates, using MOB1A/MOB1B Rabbit pAb (CAB18246) at 1:1500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Product ImageWestern blot analysis of various lysates, using MOB1A/MOB2B Rabbit pAb (CAB18246) at 1:1500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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