Cell Biology Antibodies 1

MMP7 Rabbit Polyclonal Antibody (CAB0695)

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SKU:
CAB0695
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Rat
Synonyms:
MMP-7, MPSL1, PUMP-1, MMP7
Research Use:
Cell Biology
Frequently bought together:

Description

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MMP7 Antibody (CAB0695)

The MMP7 Antibody (CAB0695) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples, making it an excellent choice for a variety of research applications.Matrilysin, also known as matrix metalloproteinase-7 (MMP-7), plays a crucial role in processes such as wound healing, inflammation, and tumor progression. By targeting the matrilysin protein, this antibody allows for the visualization and analysis of its expression in different cell types, providing valuable insights into its function.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Rat samples.

Product Name:MMP7 Antibody
SKU:CAB0695
Size:20μL, 100μL
Reactivity:Human, Rat
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:KNAN SLEA KLKE MQKF FGLP ITGM LNSR VIEI MQKP RCGV PDVA EYSL FPNS PKWT SKVV TYRI VSYT RDLP HITV DRLV SKAL NMWG KEIP LHFR KVVW G
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:200
IF/ICC1:100 - 1:500
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:MMP-7, MPSL1, PUMP-1, MMP7
Positive Sample:HT-29, 293T, A-549, Rat uterus
Cellular Localization:Secreted, Extracellular Matrix, Extracellular Space.
Calculated MW:30kDa
Observed MW:20-22kDa/28kDa

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers.

Purification MethodAffinity purification
Gene ID4316
RRIDAB_2757346
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide,pH7.3.
Product ImageWestern blot analysis of various lysates using MMP7 Rabbit pAb (CAB0695) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Product ImageWestern blot analysis of lysates from Rat uterus, using MMP7 Rabbit pAb (CAB0695) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
Product ImageImmunofluorescence analysis of A-549 cells using MMP7 Rabbit pAb (CAB0695) at dilution of 1:300 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Product ImageImmunofluorescence analysis of U2OS cells using MMP7 Rabbit pAb (CAB0695) at dilution of 1:300 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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