Cell Biology Antibodies 12

MFN1 Rabbit Polyclonal Antibody (CAB9880)

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SKU:
CAB9880
Product Type:
Antibody
Applications:
WB
Applications:
IF
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
hfzo1, hfzo2, Mitofusin-1/MFN1
Research Use:
Cell Biology
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Description

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MFN1 Antibody (CAB9880)

The MFN1 Antibody (CAB9880) is a high-quality antibody developed for reliable detection and analysis of target proteins. Mitofusin-1 is a protein involved in mitochondrial fusion, a process essential for maintaining mitochondrial health and proper cellular function. This antibody, generated in rabbits, specifically recognizes Mitofusin-1 in human samples and is validated for use in Western blot applications.By targeting Mitofusin-1, researchers can investigate the role of mitochondrial fusion in various cellular processes, including energy production, apoptosis regulation, and cellular signaling. Dysregulation of mitochondrial dynamics has been linked to a range of human diseases, making Mitofusin-1 an important target for studies in areas such as neurodegeneration, metabolic disorders, and cancer.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:MFN1 Antibody
SKU:CAB9880
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:YGAL YLYE RLSW TTHA KERA FKQQ FVNY ATEK LRMI VSST SANC SHQV KQQI ATTF ARLC QQVD ITQK QLEE EIAR LPKE IDQL EKIQ NNSK LLRN KAVQ LENE LENF TKQF LPSS NEES
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:hfzo1, hfzo2, Mitofusin-1/MFN1
Positive Sample:HeLa, T-47D, Rat heart
Cellular Localization:Cytoplasm, Mitochondrion Outer Membrane, Multi-Pass Membrane Protein.
Calculated MW:84kDa
Observed MW:84kDa

The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.

Purification MethodAffinity purification
Gene ID55669
RRIDAB_2770351
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates, using Mitofusin-1/MFN1 Rabbit pAb (CAB9880) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Product ImageWestern blot analysis of lysates from Rat heart, using Mitofusin-1/MFN1 Rabbit pAb (CAB9880) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
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