Cell Death Antibodies 2

LTBR Rabbit Polyclonal Antibody (CAB5351)

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SKU:
CAB5351
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
Reactivity:
Human, Mouse, Rat
Synonyms:
TNFCR, TNFR3, D12S370, TNFR-RP, TNFRSF3, TNFR2-RP, LT-BETA-R, TNF-R-III, LTBR
Research Use:
Cell Death
Frequently bought together:

Description

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LTBR Antibody (CAB5351)

The LTBR Antibody (CAB5351) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.LTBR is a key player in the immune system, functioning in the activation of NF-kappaB and MAPK8/JNK pathways, which are essential for cell survival and inflammation control. The LTBR Polyclonal Antibody enables precise detection and analysis of LTBR protein levels in various cell types, providing valuable insights for studies in immunology, inflammation, and autoimmunity.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:LTBR Antibody
SKU:CAB5351
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:GEQS QVAH GTNG IHVT GGSM TITG NIYI YNGP VLGG PPGP GDLP ATPE PPYP IPEE GDPG PPGL STPH QEDG KAWH LAET EHCG ATPS NRGP RNQF ITHD
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:200
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:TNFCR, TNFR3, D12S370, TNFR-RP, TNFRSF3, TNFR2-RP, LT-BETA-R, TNF-R-III, LTBR
Positive Sample:Mouse lung, Rat lung
Cellular Localization:Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:47kDa
Observed MW:47kDa

This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Purification MethodAffinity purification
Gene ID4055
RRIDAB_2766161
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using LTBR Rabbit pAb (CAB5351) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 180s.
Product ImageWestern blot analysis of lysates from Mouse brain, using LTBR Rabbit pAb (CAB5351) at 1:700 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Product ImageImmunofluorescence analysis of PC-12 cells using LTBR Rabbit pAb (CAB5351) at dilution of 1:200 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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